Invitrogen™ EphA5 Monoclonal Antibody (46CT61.6.4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA511159

Catalog No. PIMA511159

Description

EphA5 Monoclonal Antibody for Western Blot, IHC (P)

EPHA5 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e. g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e. g. ABL, FAK, JAK, and SRC families).

Specifications

• Antigen: EphA5
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P54756
• Gene Symbols: EPHA5
• Immunogen: Purified His-tagged EPHA5 protein fragment.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 46CT61.6.4
• Conjugate: Unconjugated
• Gene: EPHA5
• Gene Alias: AI854630; ARCC2; AW125296; brain-specific kinase; BSK; CEK7; CEK-7; CTPA; CTPP1; ECK; eck-like sequence 1; EHK1; EHK-1; EK7; Ekh1; Els1; Els1.; epa5; EPH homology kinase 1; Eph receptor A5; EPHA5; EPH-like kinase 7; Ephrin A2; Ephrin A5; Ephrin type-A receptor 5; EphrinA2; EphrinA5; HEK7; receptor protein-tyrosine kinase HEK7; Rek7; TYRO4; tyrosine-protein kinase receptor EHK-1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 2044
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid