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Invitrogen™ EphA5 Monoclonal Antibody (8B10B1,8B10F5)
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Catalog No. PIMA515472
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PIMA515472 100 μL
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Catalog No. PIMA515472 Supplier Invitrogen™ Supplier No. MA515472
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Description

Mouse Monoclonal Antibody

MA5-15472 targets EphA5 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15472 immunogen is purified recombinant fragment of EphA5 (aa620-774) expressed in E. Coli. .

EPHA5 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e. g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e. g. ABL, FAK, JAK, and SRC families).
TRUSTED_SUSTAINABILITY

Specifications

Antigen EphA5
Applications ELISA, Western Blot
Classification Monoclonal
Clone 8B10B1,8B10F5, 8B10F5
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene EPHA5
Gene Accession No. P54756
Gene Alias AI854630; ARCC2; AW125296; brain-specific kinase; BSK; CEK7; CEK-7; CTPA; CTPP1; ECK; eck-like sequence 1; EHK1; EHK-1; EK7; Ekh1; Els1; Els1.; epa5; EPH homology kinase 1; Eph receptor A5; EPHA5; EPH-like kinase 7; Ephrin A2; Ephrin A5; Ephrin type-A receptor 5; EphrinA2; EphrinA5; HEK7; receptor protein-tyrosine kinase HEK7; Rek7; TYRO4; tyrosine-protein kinase receptor EHK-1
Gene Symbols EPHA5
Host Species Mouse
Immunogen Purified recombinant fragment of EphA5 (aa620-774) expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2044
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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