Invitrogen™ EphA5 Polyclonal Antibody

Catalog No.	Quantity
PIPA547735	100 μg

Catalog No. PIPA547735 Supplier Invitrogen™ Supplier No. PA547735

Description

Goat Polyclonal Antibody

In direct ELISAs and Western blots, approximately 15% cross-reactivity with recombinant mouse (rm) EphA4, rmEphA3, rmEphA6, rmEphA7, rmEphA8, and recombinant rat EphB1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

EPHA5 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e. g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e. g. ABL, FAK, JAK, and SRC families).

Specifications

• Antigen: EphA5
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: EPHA5
• Gene Accession No.: P54756, P54757
• Gene Alias: AI854630; ARCC2; AW125296; brain-specific kinase; BSK; CEK7; CEK-7; CTPA; CTPP1; ECK; eck-like sequence 1; EHK1; EHK-1; EK7; Ekh1; Els1; Els1.; epa5; EPH homology kinase 1; Eph receptor A5; EPHA5; EPH-like kinase 7; Ephrin A2; Ephrin A5; Ephrin type-A receptor 5; EphrinA2; EphrinA5; HEK7; receptor protein-tyrosine kinase HEK7; Rek7; TYRO4; tyrosine-protein kinase receptor EHK-1
• Gene Symbols: EPHA5
• Host Species: Goat
• Immunogen: Mouse myeloma cell line NS0-derived recombinant rat EphA5 Met1-Gln573.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2044, 79208
• Target Species: Human, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG