Invitrogen™ EphA6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA514584

Catalog No. PIPA514584

Description

This antibody is predicted to react with rat based on sequence homology.

EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases which have been implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in nervous systems. EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia. Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context.

Specifications

• Antigen: EphA6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Epha6
• Gene Alias: DKFZp434C1418; EHK2; EHK-2; EK12; EPA6; EPH homology kinase 2; Eph receptor A6; EPHA6; EPH-like kinase 12; ephrin receptor EphA6; ephrin type-A receptor 6; FLJ35246; HEK12; m-ehk2; PRO57066; tyrosine-protein kinase receptor EHK-2
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 13840, 285220
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q62413, Q9UF33
• Gene Symbols: Epha6
• Immunogen: KLH conjugated synthetic peptide between 1006-1035 amino acids from the C-terminal region of human Eph Receptor A6.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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