Invitrogen™ EphA8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556744

Catalog No. PIPA556744

Description

Immunogen sequence: KRHCGYSKAF QDSDEEKMHY QNGQAPPPVF LPLHHPPGKL PEPQFYAQPH TYEEPGRAGR SFTREIEASR IHIEKIIGSG DSG Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

EPHA8 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA8 plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Specifications

• Antigen: EphA8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Epha8
• Gene Alias: AW047546; Eek; EK3; epa8; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; Eph receptor A8; Epha8; EPH-like kinase 3; Ephrin type-A receptor 8; Ephrin type-A receptor 8 precursor (Tyrosine-protein kinase receptor EEK) (EPH-and ELK-related kinase); Hek3; hydroxyaryl-protein kinase; KIAA1459; mKIAA1459; protein-tyrosine kinase; tyrosine-protein kinase receptor EEK; tyrosylprotein kinase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2046
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P29322
• Gene Symbols: Epha8
• Immunogen: Recombinant protein corresponding to Human EphA8. Recombinant protein control fragment (Product #RP-94014).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG