Invitrogen™ EphB2 Polyclonal Antibody

Catalog No.	Quantity
PIPA597252	100 μL

Catalog No. PIPA597252 Supplier Invitrogen™ Supplier No. PA597252

Description

Rabbit Polyclonal Antibody

Immunogen sequence: PIGRCMCKAG FEAVENGTVC RGCPSGTFKA NQGDEACTHC PINSRTTSEG ATNCVCRNGY YRADLDPLDM PCTTIPSAPQ AVISSVNETS LMLEWTPPRD SGGREDLVYN IICKSCGSGR GACTRCGDNV QYAPRQLGLT EPRIYISDLL AHTQYTFEIQ AVNGVTDQSP FSPQFASVNI TTNQAAPSAV SIMHQVSRTV DSITLSWSQP DQPNGVILDY ELQYYEKELS EYNATAIKSP TNTVTVQGLK AGAIYVFQVR ARTVAGYGRY SGKMYFQTMT EAEYQTSIQE K; Positive Samples: NCI-H460, HepG2, HeLa, HT-1080, SW620, Mouse brain, Mouse heart; Cellular Location: Cell membrane, Cell projection, Single-pass type I membrane protein, axon, dendrite.

EPHB2 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.

Specifications

• Antigen: EphB2
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1.33 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: EPHB2
• Gene Accession No.: P29323, P54763
• Gene Alias: CAPB; cEK5; chicken embryo kinase 5; chicken embryo kinase 5 protein; developmentally-regulated Eph-related tyrosine kinase; DRT; EFL6; EFNB3; EK5; ELK; ELK-related tyrosine kinase; embryo kinase 5 protein CEK5; EPH B2; EPH receptor B2; eph tyrosine kinase 3; EPHB2; EphB2/CTF1; EphB2/CTF2; EPHB3; EPH-like kinase 5; Ephrin B1; Ephrin B2; Ephrin B3; Ephrin B4; Ephrin type-B receptor 2; EphrinB1; EphrinB2; EphrinB3; EphrinB4; EPHT3; EPLG8; EPTH3; ERK; ETECK; ETK2; HEK2; Hek5; HEK-6; LERK8; MGC87492; NET; Neural kinase; Nuk; Nuk receptor tyrosine kinase; PCBC; Prkm5; protein-tyrosine kinase HEK5; Qek5; Renal carcinoma antigen NY-REN-47; RGD1564232; Sek3; TYRO5; TYRO6; Tyrosine-protein kinase receptor EPH-3; tyrosine-protein kinase receptor SEK-3; Tyrosine-protein kinase TYRO5
• Gene Symbols: EPHB2
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-540 of human EPHB2 (NP_0591452).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 13844, 2048
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov