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Invitrogen™ EphB4 Polyclonal Antibody
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Catalog No. PIPA528859
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PIPA528859 100 μL
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Catalog No. PIPA528859 Supplier Invitrogen™ Supplier No. PA528859
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (92%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

EPHB4 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EphB4
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.63 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene EPHB4
Gene Accession No. P54760
Gene Alias AI042935; Developmental kinase 2; EPH receptor B4; Ephb4; ephrin receptor EphB4; ephrin type-B receptor 4; Hepatoma transmembrane kinase; HTK; Mdk2; mDK-2; MYK1; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; TYRO11; Tyrosine kinase MYK-1; tyrosine-protein kinase receptor HTK; tyrosine-protein kinase TYRO11
Gene Symbols EPHB4
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Extracellular domain of human EphB4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2050
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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