Ephrin B1, B2, B3 Polyclonal Antibody, Rockland™

Catalog No.	Quantity
50-199-2340	100 μg
50-199-2341	25 μL

Catalog No. 50-199-2340 Supplier Rockland Immunochemicals Supplier No. 600401MP0

Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity purified antibody is directed against human Ephrin B1, B2, B3. A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with Ephrin-B1 to human, mouse, rat, and Gallus gallus; 100% homology with Ephrin-B2 to mouse; 100% homology with Ephrin-B3 to human and mouse.

Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.

Specifications

• Antigen: Ephrin B1, B2, B3
• Applications: ELISA, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: 1.05 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene: EFNB1
• Gene Accession No.: O35393, P52795, P52799, P52800, P98172, Q15768
• Gene Alias: CEK5 receptor ligand; CEK5-L; CFND; CFNS; EFB1; EFL3; EFL-3; EFL6; EFL-6; Efnb1; Efnb2; Efnb3; Elf2; ELF-2; ELF-3; ELK ligand; ELK-L; Elk-L3; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 2; EPH-related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 8; ephrin B1; ephrin B2; ephrin B3; ephrin ligand B3; Ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B2; Ephrin-B3; Epl2; Epl5; Epl8; Eplg2; EPLG5; EPLG8; HTK ligand; HTKL; HTK-L; Lerk2; LERK-2; Lerk5; LERK-5; LERK8; LERK-8; ligand of eph-related kinase 5; NLERK-1; NLERK-2; Stimulated by retinoic acid gene 1 protein; Stra1
• Gene Symbols: EFNB1, EFNB2, EFNB3
• Host Species: Rabbit
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 13641, 13642, 13643, 1947, 1948, 1949, 779011
• Target Species: Human, Mouse, X. laevis
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid