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Ephrin B1, B2, B3 Polyclonal Antibody, Rockland™
SDP

Catalog No. 501992341
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100 μg
25 μL
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50-199-2341 25 μL
50-199-2340 100 μg
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Catalog No. 50-199-2341 Supplier Rockland Immunochemicals Supplier No. 600401MP0S
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Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity purified antibody is directed against human Ephrin B1, B2, B3. A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with Ephrin-B1 to human, mouse, rat, and Gallus gallus; 100% homology with Ephrin-B2 to mouse; 100% homology with Ephrin-B3 to human and mouse.

Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.

Specifications

Antigen Ephrin B1, B2, B3
Applications ELISA, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 1.05 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene EFNB1
Gene Accession No. O35393, P52795, P52799, P52800, P98172, Q15768
Gene Alias CEK5 receptor ligand; CEK5-L; CFND; CFNS; EFB1; EFL3; EFL-3; EFL6; EFL-6; Efnb1; Efnb2; Efnb3; Elf2; ELF-2; ELF-3; ELK ligand; ELK-L; Elk-L3; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 2; EPH-related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 8; ephrin B1; ephrin B2; ephrin B3; ephrin ligand B3; Ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B2; Ephrin-B3; Epl2; Epl5; Epl8; Eplg2; EPLG5; EPLG8; HTK ligand; HTKL; HTK-L; Lerk2; LERK-2; Lerk5; LERK-5; LERK8; LERK-8; ligand of eph-related kinase 5; NLERK-1; NLERK-2; Stimulated by retinoic acid gene 1 protein; Stra1
Gene Symbols EFNB1, EFNB2, EFNB3
Host Species Rabbit
Quantity 25 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13641, 13642, 13643, 1947, 1948, 1949, 779011
Target Species Human, Mouse, X. laevis
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
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