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Invitrogen™ Ephrin B3 Polyclonal Antibody
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Catalog No. PIPA597697
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100 μg
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PIPA597697 100 μg
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Catalog No. PIPA597697 Supplier Invitrogen™ Supplier No. PA597697
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Description

Rabbit Polyclonal Antibody

Ephrin B3 Polyclonal Antibody for Western Blot, ELISA

EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ephrin B3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene EFNB3
Gene Accession No. O35393, Q15768
Gene Alias EFL6; EFL-6; Efnb3; ELF-3; Elk-L3; EPH-related receptor transmembrane ligand ELK-L3; eph-related receptor tyrosine kinase ligand 8; ephrin B3; ephrin ligand B3; ephrin-B3; Epl8; EPLG8; LERK8; LERK-8; NLERK-2
Gene Symbols EFNB3
Host Species Rabbit
Immunogen Recombinant Mouse Ephrin-B3 protein (28-227AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13643, 1949
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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