(-)-Epicatechin Gallate, PROMO, Thermo Scientific Chemicals

Description

A natural product from green tea that induces apoptosis

Applications

(-)-Epicatechin gallate is used as an antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression. One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency.

Solubility

Soluble in water, acetone, DMSO, methanol.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 to 8°C

Specifications

Chemical Identifiers

• CAS: 1257-08-5
• Molecular Formula: C22H18O10
• Molecular Weight (g/mol): 442.38 g/mol
• MDL Number: MFCD00075936
• InChI Key: LSHVYAFMTMFKBA-TZIWHRDSSA-N
• Synonym: =--epicatechin gallate, epicatechin gallate, =--epicatechin-3-o-gallate, l-epicatechin gallate, =--epicatechin-3-gallate, =--epicatechingallate, epicatechin monogallate, --epicatechin 3-o-gallate, teatannin, epicatechol, gallate
• PubChem CID: 107905
• ChEBI: CHEBI:70255
• IUPAC Name: [(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
• SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O

• Color: White
• Quantity: 10 mg
• Solubility Information: Soluble in water, acetone, DMSO, methanol.
• Physical Form: Powder
• Chemical Name or Material: (-)-Epicatechin gallate

Safety and Handling

RTECSNumber	DH9030000
TSCA	No
Recommended Storage	Keep cold

RUO - Research Use Only