Invitrogen™ Epiregulin Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5119096	Invitrogen™ PA5119096	200 μL
PIPA5122013	Invitrogen™ PA5122013	20 μL

Description

Epiregulin Polyclonal Antibody for Western Blot

Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.

Specifications

• Antigen: Epiregulin
• Content And Storage: -20°C
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: Ereg
• Gene Alias: Ep; Epiregulin; EPR; ER; EREG; Proepiregulin
• Gene Symbols: Ereg
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography

• Concentration: 0.5 mg/mL
• Applications: Western Blot, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: O14944
• Gene ID (Entrez): 2069
• Immunogen: Recombinant protein Epiregulin. The antigen corresponds to amino acid range 30-169 of the target protein.
• Product Type: Antibody