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Invitrogen™ Epiregulin Polyclonal Antibody
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Catalog No. PIPA5121403
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100 μL
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PIPA5121403 100 μL
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Catalog No. PIPA5121403 Supplier Invitrogen™ Supplier No. PA5121403
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Description

Rabbit Polyclonal Antibody

Antibody tested in Indirect ELISA.

Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Epiregulin
Applications ELISA, Immunocytochemistry
Classification Polyclonal
Concentration 5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Ereg
Gene Accession No. O14944
Gene Alias Ep; Epiregulin; EPR; ER; EREG; Proepiregulin
Gene Symbols Ereg
Host Species Rabbit
Immunogen Recombinant Human Proepiregulin protein (144-160aa).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2069
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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