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Invitrogen™ EPM2A Polyclonal Antibody
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Catalog No. PIPA5111374
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100 μL
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PIPA5111374 100 μL
PIPA5111418 100 μL
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Catalog No. PIPA5111374 Supplier Invitrogen™ Supplier No. PA5111374
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ATGHTNEMKH TTDFYFNIAG HQAMHYSRIL PNIWLGSCPR QVEHVTIKLK HELGITAVMN FQTEWDIVQN SSGCNRYPEP MTPDTMIKLY REEGLAYIWM PTPDMSTEGR VQMLP Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 95%.

The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EPM2A
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene EPM2A
Gene Accession No. O95278
Gene Alias epilepsy, progressive myoclonic epilepsy, type 2 gene alpha; epilepsy, progressive myoclonus type 2, Lafora disease (laforin); epilepsy, progressive myoclonus type 2A; epilepsy, progressive myoclonus type 2A, Lafora disease (laforin); EPM2; EPM2A; EPM2A glucan phosphatase, laforin; EPM2A, laforin glucan phosphatase; glucan phosphatase; Glycogen phosphatase; Lafora PTPase; laforin; LAFPTPase; MELF; RP1-28C20.2; Tg(TcraK,TcrbK)TG-BFlv; TG-B
Gene Symbols EPM2A
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human EPM2A. Recombinant protein control fragment (Product #RP-91068).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7957
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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