Invitrogen™ EPM2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5111374	Invitrogen™ PA5111374	100 μL
PIPA5111418	Invitrogen™ PA5111418	100 μL

Description

Immunogen sequence: ATGHTNEMKH TTDFYFNIAG HQAMHYSRIL PNIWLGSCPR QVEHVTIKLK HELGITAVMN FQTEWDIVQN SSGCNRYPEP MTPDTMIKLY REEGLAYIWM PTPDMSTEGR VQMLP.

The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.

Specifications

• Antigen: EPM2A
• Applications: Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95278
• Gene ID (Entrez): 7957
• Immunogen: Recombinant Protein corresonding to Human EPM2A. Recombinant protein control fragment (Product #RP-91068).
• Product Type: Antibody

• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: EPM2A
• Gene Alias: epilepsy, progressive myoclonic epilepsy, type 2 gene alpha; epilepsy, progressive myoclonus type 2, Lafora disease (laforin); epilepsy, progressive myoclonus type 2A; epilepsy, progressive myoclonus type 2A, Lafora disease (laforin); EPM2; EPM2A; EPM2A glucan phosphatase, laforin; EPM2A, laforin glucan phosphatase; glucan phosphatase; Glycogen phosphatase; Lafora PTPase; laforin; LAFPTPase; MELF; RP1-28C20.2; Tg(TcraK,TcrbK)TG-BFlv; TG-B
• Gene Symbols: EPM2A
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography