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Invitrogen™ Epo Monoclonal Antibody (4F11)
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Catalog No. PIMA515684
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100 μL
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Catalog No. Quantity
PIMA515684 100 μL
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Catalog No. PIMA515684 Supplier Invitrogen™ Supplier No. MA515684
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Description

Mouse Monoclonal Antibody

MA5-15684 targets EPO in indirect ELISA, IF and WB applications and shows reactivity with Human samples. The MA5-15684 immunogen is purified recombinant fragment of human EPO expressed in E. Coli. MA5-15684 detects EPO which has a predicted molecular weight of approximately 21kDa.

Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through adulthood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Epo
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4F11
Concentration Conc. not determined
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene EPO
Gene Accession No. P01588
Gene Alias EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2
Gene Symbols EPO
Host Species Mouse
Immunogen Purified recombinant fragment of human EPO expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2056
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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