EPO Monoclonal Antibody (OTI5D8), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-4397	100 μL

Catalog No. 50-168-4397 Supplier OriGene Supplier No. TA812059

Description

Mouse Monoclonal Antibody

Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through adulthood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.

Specifications

• Antigen: EPO
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI5D8
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: EPO
• Gene Accession No.: P01588
• Gene Alias: EP, MVCD2
• Gene Symbols: EPO
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 28-193 of human EPO produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2056
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1