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Invitrogen™ Epo Polyclonal Antibody
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Catalog No. PIPA579212
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100 μg
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PIPA579212 100 μg
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Catalog No. PIPA579212 Supplier Invitrogen™ Supplier No. PA579212
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Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - IHC: Human Placenta Tissue.

Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through adulthood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Epo
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 0.05mg sodium azide
Gene EPO
Gene Accession No. P01588
Gene Alias EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2
Gene Symbols EPO
Host Species Rabbit
Immunogen E. coli-derived human EPO recombinant protein (Position: M1-R166).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2056
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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