Invitrogen™ Epratuzumab Chimeric Recombinant Rabbit Monoclonal Antibody (hL22 (Epratuzumab))

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA548052

Catalog No. PIMA548052

Description

Specificity: This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells.

Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.

Specifications

• Antigen: Epratuzumab Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Human, Rhesus Macaque, Cynomolgus Monkey
• Product Type: Antibody
• Isotype: IgG κ

• Applications: Flow Cytometry, Inhibition Assays, Immunoprecipitation
• Clone: hL22 (Epratuzumab)
• Conjugate: Unconjugated
• Gene Alias: 90Y-DOTA-hLL2; 90Y-epratuzumab tetraxetan; 90Y-hLL2; AMG-412; hLL2
• Immunogen: This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid