Invitrogen™ EPS15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577967

Catalog No. PIPA577967

Description

Positive Control: Raji, K562, BCL-1 Predicted Reactivity: Chicken (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.

Specifications

• Antigen: EPS15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPS15
• Gene Alias: 2410112D09Rik; AF1P; AF-1P; AF-1p protein; ALL1 fused gene from chromosome 1; epidermal growth factor pathway substrate 15; epidermal growth factor receptor pathway substrate 15; epidermal growth factor receptor substrate 15; EPS15; MLLT5; protein AF-1p; Protein Eps15; RGD1307641
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13858, 2060
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.83 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol, 0.1M glycine and 0.01% thimerosal; pH 7
• Gene Accession No.: P42566, P42567
• Gene Symbols: EPS15
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Eps15. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG