Invitrogen™ EPS15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579216

Catalog No. PIPA579216

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human A375 whole cell, human HepG2 whole cell, human Jurkat whole cell, human PANC-1 whole cell, rat brain tissue, rat liver tissue, mouse brain tissue, mouse spleen tissue, mouse liver tissue, mouse testis tissue.

EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.

Specifications

• Antigen: EPS15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPS15
• Gene Alias: 2410112D09Rik; AF1P; AF-1P; AF-1p protein; ALL1 fused gene from chromosome 1; epidermal growth factor pathway substrate 15; epidermal growth factor receptor pathway substrate 15; epidermal growth factor receptor substrate 15; EPS15; MLLT5; protein AF-1p; Protein Eps15; RGD1307641
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13858, 2060, 313474
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P42566, P42567
• Gene Symbols: EPS15
• Immunogen: E. coli-derived human EPS15 recombinant protein (Position: A2-E88).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov