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Invitrogen™ EPS15 Polyclonal Antibody
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Catalog No. PIPA582353
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100 μL
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PIPA582353 100 μL
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Catalog No. PIPA582353 Supplier Invitrogen™ Supplier No. PA582353
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CFFRQSTDPF ATSSTDPFSA ANNSSITSVE TLKHNDPFAP GGTVVAASDS ATDPFASVFG NESFGGGFAD FSTLSKVNNE DPFRSATSSS VSNVVITKNV FEETSVKSED EPPALPPKIG TPTRPCPLPP GKRSINKLDS PD Highest antigen sequence indentity to the following orthologs: Mouse - 81%, Rat - 83%.

EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EPS15
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene EPS15
Gene Accession No. P42566
Gene Alias 2410112D09Rik; AF1P; AF-1P; AF-1p protein; ALL1 fused gene from chromosome 1; epidermal growth factor pathway substrate 15; epidermal growth factor receptor pathway substrate 15; epidermal growth factor receptor substrate 15; EPS15; MLLT5; protein AF-1p; Protein Eps15; RGD1307641
Gene Symbols EPS15
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human EPS15. Recombinant protein control fragment (Product #RP-89543).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2060
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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