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Invitrogen™ EPS15 Polyclonal Antibody
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Catalog No. PIPA597253
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100 μL
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PIPA597253 100 μL
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Catalog No. PIPA597253 Supplier Invitrogen™ Supplier No. PA597253
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RQSTDPFATS STDPFSAANN SSITSVETLK HNDPFAPGGT VVAASDSATD PFASVFGNES FGGGFADFST LSKVNNEDPF RSATSSSVSN VVITKNVFEE TSVKSEDEPP ALPPKIGTPT RPCPLPPGKR SINKLDSPDP FKLNDPFQPF PGNDSPKEKD PEIFCDPFTS ATTTTNKEAD P; Positive Samples: HeLa, Jurkat, 293T, NIH/3T3, Mouse liver, Mouse spleen, Mouse lung; Cellular Location: Cell membrane, Cytoplasm, Cytoplasmic side, Early endosome membrane, Membrane, Peripheral membrane protein, clathrin-coated pit.

EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EPS15
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.82 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene EPS15
Gene Accession No. P42566, P42567
Gene Alias 2410112D09Rik; AF1P; AF-1P; AF-1p protein; ALL1 fused gene from chromosome 1; epidermal growth factor pathway substrate 15; epidermal growth factor receptor pathway substrate 15; epidermal growth factor receptor substrate 15; EPS15; MLLT5; protein AF-1p; Protein Eps15; RGD1307641
Gene Symbols EPS15
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13858, 2060, 313474
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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