Invitrogen™ EPS15R Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553965

Catalog No. PIPA553965

Description

Immunogen sequence: KQDAQDRLDE MDQQKAKLRD MLSDVRQKCQ DETQMISSLK TQIQSQESDL KSQEDDLNRA KSELNRLQQE ETQLEQSIQA GRVQLETIIK SLKSTQDEIN QARSKLSQ Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. [UniProt].

Specifications

• Antigen: EPS15R
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPS15L1
• Gene Alias: 9830147J04Rik; AI593686; epidermal growth factor receptor pathway substrate 15 like 1; epidermal growth factor receptor pathway substrate 15-like 1; epidermal growth factor receptor pathway substrate 15-related sequence; Epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; Eps15l1; EPS15R; eps15-related protein; Eps15-rs
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58513
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.6 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UBC2
• Gene Symbols: EPS15L1
• Immunogen: Recombinant protein corresponding to Human EPS15R. Recombinant protein control fragment (Product #RP-92469).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG