Invitrogen™ Epsin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590935

Catalog No. PIPA590935

Description

Immunogen sequence: GINVREKSKQ LVALLKDEER LKAERAQALK TKERMAQVAT GMGSNQITFG RGSSQPNLST SHSEQEYGKA GGSPASYHGS TSPRVSSELE QARPQTSGEE ELQLQLALAM SREVAEQEER LRRGDDLRLQ MALEESRRDT VKIPKKKEHG SLPQQTTLLD LMDALPSSGP AAQKAEPWGP S; Positive Samples: U-87MG, LO2, HeLa; Cellular Location: Cytoplasm, Cytoplasmic vesicle, clathrin-coated vesicle.

Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.

Specifications

• Antigen: Epsin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPN2
• Gene Alias: 9530051D10Rik; AA536924; EH domain binding protein epsin 2; EHB21; EPN2; Eps15 binding protein; EPS-15-interacting protein 2; epsin 2; epsin-2; Ibp2; Intersectin-EH-binding protein 2; KIAA1065
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22905
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 3.48 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O95208
• Gene Symbols: EPN2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-300 of human EPN2 (NP_6837232).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG