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Invitrogen™ Epstein Barr Virus Bcl-2 Monoclonal Antibody (D44E)
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Catalog No. PIMA17275
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100 μg
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Catalog No. Quantity
PIMA17275 100 μg
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Catalog No. PIMA17275 Supplier Invitrogen™ Supplier No. MA17275
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Description

Mouse Monoclonal Antibody

The MA1-7275 antibody reacts with Epstein-Barr virus Bcl-2 in viral and infected tissue samples. MA1-7275 has been successfully used in ELISA, Western blot, Immunohistochemical and Immunoprecipitation applications. The MA1-7275 antibody was raised against EBV BCl-2 homolog protein.

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
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Specifications

Antigen Epstein Barr Virus Bcl-2
Applications ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone D44E
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.2
Gene Alias EBV; EBV bcl2; EBV Bcl-2
Host Species Mouse
Immunogen EBV BCl-2 homolog.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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