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Invitrogen™ Epstein Barr Virus Ea-D Monoclonal Antibody (H11B)
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Catalog No. MA17277
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100 μg
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Catalog No. Quantity
MA17277 100 μg
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Catalog No. MA17277 Supplier Invitrogen™ Supplier No. MA17277
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Mouse Monoclonal Antibody

The MA1-7277 antibody reacts with Epstein-Barr virus EA-D in viral and infected tissue samples. MA1-7277 has been successfully used in Western blot, Immunofluorescence and Immunohistochemical applications. The MA1-7277 antibody was raised against EBV EA-D protein.

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Epstein Barr Virus Ea-D
Applications Immunohistochemistry, Western Blot
Classification Monoclonal
Clone H11B
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.2
Gene Alias EBV; EBV EA; EBV EAD; EBV early
Host Species Mouse
Immunogen EBV EA-D.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2
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