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Invitrogen™ Epstein Barr Virus Nuclear Antigen 1 Polyclonal Antibody, Biotin
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Catalog No. PA17499
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1 mL
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PA17499 1 mL
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Catalog No. PA17499 Supplier Invitrogen™ Supplier No. PA17499
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Description

Goat Polyclonal Antibody

The PA1-7499 antibody reacts with Epstein-Barr virus EBNA-1. PA1-7499 has been successfully used in Immunohistochemical, ELISA, Immunofluorescence and Western blot applications. The PA1-7499 antibody was raised against Recombinant EBV EBNA-1. Store at 4°C for up to 6 months. For long term storage, aliquot and freeze at -20°C. Avoid freeze-thaw cycles.

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Epstein Barr Virus Nuclear Antigen 1
Applications ELISA
Classification Polyclonal
Concentration 5 mg/mL
Conjugate Biotin
Formulation PBS with 0.1% sodium azide; pH 7.2
Gene Alias EBNA-1
Host Species Goat
Immunogen Purified recombinant EBV EBNA-1.
Purification Method IgG fraction
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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