Invitrogen™ ERAL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587857

Catalog No. PIPA587857

Description

Immunogen sequence: DLVVVLVDVS DKWTRNQLSP QLLRCLTKYS QIPSVLVMNK VDCLKQKSVL LELTAALTEG VVNGKKLKMR QAFHSHPGTH CPSPAVKDPN TQSVGNPQRI GWPHFKEIFM LSALSQEDVK TLKQYLLTQA QPGPWEYHSA VLTSQTPEEI CANIIREKLL EHLPQEVPYN VQQKTAVWEE GPGGELVIQQ KLLVPKESYV KLLIGPKGHV ISQIAQEAGH DLMDIFLCDV DIRLSVKLLK; Positive Samples: SKOV3, HeLa, U-87MG, NCI-H460, Mouse kidney, Mouse heart, Rat liver; Cellular Location: Mitochondrion inner membrane, Mitochondrion matrix, Peripheral membrane protein.

The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: ERAL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ERAL1
• Gene Alias: 2610524P08Rik; 9130407C09Rik; AU019798; CEGA; Conserved ERA-like GTPase; ERA; era (E. coli G-protein homolog)-like 1; Era (G-protein)-like 1; Era (G-protein)-like 1 (E. coli); Era G-protein-like 1; Era like 12S mitochondrial rRNA chaperone 1; Eral1; ERAL1A; Era-like 1; Era-like 12S mitochondrial rRNA chaperone 1; ERA-like GTPase; ERA-like protein 1; ERA-W; GTPase Era, mitochondrial; GTPase, human homolog of E. coli essential cell cycle protein Era; GTP-binding protein era homolog; HERA; H-ERA; HERA-A; HERA-B; Mera; M-ERA; MERA-S; MERA-W
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26284
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.04 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O75616
• Gene Symbols: ERAL1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 198-437 of human ERAL1 (NP_0056931).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG