ERAS/HRAS2 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-6233	100 μL

Catalog No. 50-198-6233 Supplier Bioss Supplier No. BS4950R

Description

Rabbit Polyclonal Antibody

The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11.23.

Specifications

• Antigen: ERAS/HRAS2
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ERAS
• Gene Accession No.: Q7Z444
• Gene Alias: ecat5; Embryonic stem cell-expressed Ras; ERAS; E-Ras; ES cell expressed Ras; ES cell-expressed Ras; GTPase ERas; Ha-Ras2; HRAS2; HRASP; small GTPase E-Ras; small GTPase protein E-Ras; v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2; v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene
• Gene Symbols: ERAS
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human ERAS/HRAS2.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3266
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG