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Invitrogen™ ERAS Monoclonal Antibody (D10-B9)
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Catalog No. PIMA532907
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100 μL
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PIMA532907 100 μL
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Catalog No. PIMA532907 Supplier Invitrogen™ Supplier No. MA532907
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Description

Mouse Monoclonal Antibody

ERAS Monoclonal Antibody for ICC/IF, IHC (P)

The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11.23.
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Specifications

Antigen ERAS
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Immunohistochemistry
Classification Monoclonal
Clone D10-B9
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene ERAS
Gene Accession No. Q7Z444
Gene Alias ecat5; Embryonic stem cell-expressed Ras; ERAS; E-Ras; ES cell expressed Ras; ES cell-expressed Ras; GTPase ERas; Ha-Ras2; HRAS2; HRasp; small GTPase E-Ras; small GTPase protein E-Ras; v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2; v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene
Gene Symbols ERAS
Host Species Mouse
Immunogen Recombinant protein within Human ERAS aa 1-233.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3266
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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