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ERAS Mouse anti-Human, Clone: OTI3A3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF503753

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11.23.Specifications
ERAS | |
Monoclonal | |
Unconjugated | |
ERAS | |
HRAS2, HRASP | |
Mouse | |
Affinity Chromatography | |
RUO | |
3266 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot | |
OTI3A3 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q7Z444 | |
ERAS | |
Full length human recombit protein of human ERAS produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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