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ERAS Mouse anti-Human, Clone: OTI3A3, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF503753

Encompass_Preferred

Catalog No. 50-166-2362


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11.23.
Specifications

Specifications

ERAS
Monoclonal
Unconjugated
ERAS
HRAS2, HRASP
Mouse
Affinity Chromatography
RUO
3266
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI3A3
PBS with 8% trehalose and no preservative; pH 7.3
Q7Z444
ERAS
Full length human recombit protein of human ERAS produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG1
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