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Invitrogen™ ERAS Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA581382
Description
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Mouse ERAS.
The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2), with several base substitutions in coding regions, but was more recently described as potentially encoding a functional human ERAS protein. The ERAS oncogene supports the tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein. ERAS protein has less than 50% amino acid identity with H-Ras, another member of Ras family but the key domains essential for Ras function are highly conserved. The protein also contains amino-acid residues identical to those present in active mutants of Ras and causes oncogenic transformation in NIH 3T3 cells. Human ERAS gene is localized in the chromosomal region Xp11.23.
Specifications
ERAS | |
Polyclonal | |
Unconjugated | |
ERAS | |
ecat5; Embryonic stem cell-expressed Ras; ERAS; E-Ras; ES cell expressed Ras; ES cell-expressed Ras; GTPase ERas; Ha-Ras2; HRAS2; HRasp; small GTPase E-Ras; small GTPase protein E-Ras; v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2; v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene | |
Rabbit | |
Antigen Affinity Chromatography, Protein A | |
RUO | |
353283 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with no preservative | |
Q7TN89 | |
ERAS | |
A synthetic peptide corresponding to the center region of the Mouse ERAS. | |
100 μL | |
Primary | |
Mouse | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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