ErbB2/Her2 Mouse, Clone: HRB2/258, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP232862F	Novus Biologicals NBP2328620.02MG	0.02 mg
NBP232862A	Novus Biologicals NBP2328620.1MG	0.1 mg
NBP232862B	Novus Biologicals NBP2328620.2MG	0.2 mg

Description

ErbB2/Her2 Monoclonal specifically detects ErbB2/Her2 in Human, Mouse, Rat samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: ErbB2/Her2
• Dilution: Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, SDS-Page
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human, Rat
• Gene Accession No.: P04626
• Gene ID (Entrez): 2064
• Immunogen: Recombinant extracellular domain of human HER-2 protein
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.
• Molecular Weight of Antigen: 185 kDa

• Clone: HRB2/258
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, SDS-Page
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Breast Cancer, Cancer, Cellular Markers, Core ESC Like Genes, Phospho Specific, Protein Kinase, Stem Cell Markers, Tumor Suppressors
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)
• Gene Symbols: ERBB2
• Isotype: IgG2a κ
• Purification Method: Protein A purified
• Test Specificity: Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. C-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.