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ERCC1 Monoclonal Antibody (3H11), Invitrogen™

Catalog No. PIMA513830
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500 μL
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Catalog No. Quantity
PIMA513830 500 μL
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Catalog No. PIMA513830 Supplier Thermo Scientific Supplier No. MA513830
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Description

Mouse Monoclonal Antibody

MA5-13830 targets ERCC1 in IP and WB applications and shows reactivity with Human samples. The MA5-13830 immunogen is full length recombinant human ERCC1 protein.

ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. It is responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). It participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. (Uniprot)
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERCC1
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 3H11
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene ERCC1
Gene Accession No. P07992
Gene Alias COFS4; DNA excision repair protein ERCC-1; ERCC excision repair 1, endonuclease non-catalytic subunit; Ercc1; Ercc-1; excision repair cross-complementation group 1; excision repair cross-complementing 1; excision repair cross-complementing rodent repair deficiency, complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); hypothetical protein LOC405807; RAD10; UV20; zgc:77511
Gene Symbols ERCC1
Host Species Mouse
Immunogen Full length recombinant human ERCC1 protein
Purification Method Protein A
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2067
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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