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ERCC1 Mouse anti-Human, Clone: OTI1A1, lyophilized, TrueMAB™
SDP

Catalog No. 501662777
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100 μg
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Catalog No. Quantity
50-166-2777 100 μg
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Catalog No. 50-166-2777 Supplier OriGene Supplier No. CF504288
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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3′ of the DNA lesion while the ERCC1-XPF complex makes the 5′ incision.

Specifications

Antigen ERCC1
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone OTI1A1
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene ERCC1
Gene Accession No. P07992
Gene Alias COFS4, RAD10, UV20
Gene Symbols ERCC1
Host Species Mouse
Immunogen Full length human recombit protein of human ERCC1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2067
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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