ERCC1 Mouse anti-Human, Clone: OTI2A8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF504287

Catalog No. 50-166-2776

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3′ of the DNA lesion while the ERCC1-XPF complex makes the 5′ incision.

Specifications

• Antigen: ERCC1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ERCC1
• Gene Alias: COFS4, RAD10, UV20
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2067
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI2A8
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P07992
• Gene Symbols: ERCC1
• Immunogen: Full length human recombit protein of human ERCC1 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1