ERCC2 Monoclonal Antibody (OTI4B11), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA804192

Catalog No. 50-168-0118

Description

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: ERCC2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P18074
• Gene Symbols: ERCC2
• Immunogen: Human recombit protein fragment corresponding to amino acids 78-307 of human ERCC2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: OTI4B11
• Conjugate: Unconjugated
• Gene: ERCC2
• Gene Alias: COFS2, EM9, TFIIH, TTD, TTD1, XPD
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2068
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid