ERCC2 Mouse anti-Human, Clone: OTI4B11, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-6862	100 μg

Catalog No. 50-166-6862 Supplier OriGene Supplier No. CF804192

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: ERCC2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI4B11
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: ERCC2
• Gene Accession No.: P18074
• Gene Alias: COFS2, EM9, TFIIH, TTD, TTD1, XPD
• Gene Symbols: ERCC2
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 78-307 of human ERCC2 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2068
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2a