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Invitrogen™ ERCC6L Polyclonal Antibody
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Catalog No. PA550405
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100 μL
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PA550405 100 μL
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Catalog No. PA550405 Supplier Invitrogen™ Supplier No. PA550405
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total ERCC6L protein.

ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint. ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERCC6L
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Ercc6l
Gene Accession No. Q2NKX8
Gene Alias ATP-dependent helicase ERCC6-like; BC004701; D330021P09Rik; DNA excision repair protein ERCC-6-like; ERCC excision repair 6 like, spindle assembly checkpoint helicase; ERCC6L; excision repair cross-complementation group 6 like; excision repair cross-complementation group 6-like; excision repair cross-complementing rodent repair deficiency complementation group 6 - like; excision repair cross-complementing rodent repair deficiency complementation group 6 like; excision repair cross-complementing rodent repair deficiency complementation group 6-like; excision repair cross-complementing rodent repair deficiency, complementation group 6-like; excision repair protein ERCC6-like; FLJ20105; LOW QUALITY PROTEIN: DNA excision repair protein ERCC-6-like; MGC131695; PICH; PLK1-interacting checkpoint helicase; RAD26L; RGD1565734; SNF2/RAD54 family protein; tumor antigen BJ-HCC-15
Gene Symbols Ercc6l
Host Species Rabbit
Immunogen Fusion protein corresponding to residues near the C terminal of human excision repair cross-complementation group 6-like.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54821
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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