Invitrogen™ ERCC6L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550405

Catalog No. PA550405

Description

The antibody detects endogenous levels of total ERCC6L protein.

ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint. ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

Specifications

• Antigen: ERCC6L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ercc6l
• Gene Alias: ATP-dependent helicase ERCC6-like; BC004701; D330021P09Rik; DNA excision repair protein ERCC-6-like; ERCC excision repair 6 like, spindle assembly checkpoint helicase; ERCC6L; excision repair cross-complementation group 6 like; excision repair cross-complementation group 6-like; excision repair cross-complementing rodent repair deficiency complementation group 6 - like; excision repair cross-complementing rodent repair deficiency complementation group 6 like; excision repair cross-complementing rodent repair deficiency complementation group 6-like; excision repair cross-complementing rodent repair deficiency, complementation group 6-like; excision repair protein ERCC6-like; FLJ20105; LOW QUALITY PROTEIN: DNA excision repair protein ERCC-6-like; MGC131695; PICH; PLK1-interacting checkpoint helicase; RAD26L; RGD1565734; SNF2/RAD54 family protein; tumor antigen BJ-HCC-15
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54821
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q2NKX8
• Gene Symbols: Ercc6l
• Immunogen: Fusion protein corresponding to residues near the C terminal of human excision repair cross-complementation group 6-like.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG