Invitrogen™ ERCC8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA580596

Catalog No. PIPA580596

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human ERCC8.

This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

Specifications

• Antigen: ERCC8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ERCC8
• Gene Alias: 2410022P04Rik; 2810431L23Rik; 4631412O06Rik; B130065P18Rik; Ckn1; Cockayne syndrome 1 (classical); Cockayne syndrome 1 homolog; cockayne syndrome WD repeat protein CSA; Cockayne syndrome WD repeat protein CSA homolog; Cockayne syndrome WD-repeat protein CSA; CSA; DNA excision repair protein ERCC-8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit; Ercc8; excision repair cross-complementation group 8; excision repair cross-complementing rodent repair deficiency complementation group 8; excision repair cross-complementing rodent repair deficiency, complementation group 8; excision repaiross-complementing rodent repair deficiency, complementation group 8; UVSS2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1161
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q13216
• Gene Symbols: ERCC8
• Immunogen: A synthetic peptide corresponding to the C-terminus of the human ERCC8.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov