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ERCC8 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA521284
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PIPA521284 100 μL
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Catalog No. PIPA521284 Supplier Thermo Scientific Supplier No. PA521284

Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Neuro2A, GL261, C8D30, NIH-3T3, Raw264.7, C2C12. Predicted reactivity: Mouse (93%), Rat (96%), Xenopus laevis (83%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to μgtraviolet radiation and are defective in the repair of transcriptionally active genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ERCC8
Applications Functional Assay, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene ERCC8
Gene Accession No. Q13216, Q8CFD5
Gene Alias 2410022P04Rik; 2810431L23Rik; 4631412O06Rik; B130065P18Rik; Ckn1; Cockayne syndrome 1 (classical); Cockayne syndrome 1 homolog; cockayne syndrome WD repeat protein CSA; Cockayne syndrome WD repeat protein CSA homolog; Cockayne syndrome WD-repeat protein CSA; CSA; DNA excision repair protein ERCC-8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit; Ercc8; excision repair cross-complementation group 8; excision repair cross-complementing rodent repair deficiency complementation group 8; excision repair cross-complementing rodent repair deficiency, complementation group 8; excision repaiross-complementing rodent repair deficiency, complementation group 8; UVSS2
Gene Symbols ERCC8
Host Species Rabbit
Immunogen Recombinant fragment corresponding to a region within amino acids 106 and 330 of CSA (Uniprot ID#Q13216)
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1161, 71991
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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