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Tocris Bioscience™ ERGi-USU

Catalog No. 663250
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50 mg
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Catalog No. Quantity
66-325-0 50 mg
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Catalog No. 66-325-0 Supplier Tocris Bioscience™ Supplier No. 6632/50
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Description

Rio2 kinase (RIOK2) inhibitor

ERGi-USU is a high affinity Rio Kinase 2 (RIOK2) inhibitor (Kd = 200 nM). Exhibits >6-fold selectivity for RIOK2 over a panel of 456 kinases. Inhibits ERG protein and potently inhibits growth of ERG-positive VCaP prostate cancer cells in vitro (IC50 = 169 nM) but not ERG-negative cell lines. Also inhibits growth of VCaP xenografts in mice.

Specifications

Chemical Name or Material 1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol
CAS 1147-56-4
Quantity 50 mg
Molecular Formula C13H9N3OS
Formula Weight 255.3
Purity 99%
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