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Invitrogen™ ERK1 Monoclonal Antibody (7-D6-E5)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA544615
This item is not returnable.
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Description
ERK1 Monoclonal Antibody for Western Blot, ICC/IF
MAPK3 (ERK1) is a serine/threonine kinase that is an important activator of p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. ERK1 is widely expressed and involved in the regulation of meiosis, mitosis, and post-mitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways. Functionally, ERK1 is involved with a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. ERK1 is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms of ERK1 have been described.
Specifications
ERK1 | |
Monoclonal | |
2 mg/mL | |
PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 | |
P21708, P27361, Q63844 | |
MAPK3 | |
Synthetic peptide within Human ERK1 aa 301-350/379. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG1 |
Western Blot, Immunocytochemistry | |
7-D6-E5 | |
Unconjugated | |
MAPK3 | |
ERK; Erk1; ERK-1; Ert2; Esrk1; Extracellular signal-regulated kinase 1; extracellular signal-related kinase 1; HS44KDAP; HUMKER1A; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; MAP kinase2; MAPK 1; MAPK 3; MAPK1; MAPK2; MAPK3; Microtubule-associated protein 2 kinase; mitogen activated protein kinase 3; mitogen-activated 3; mitogen-activated protein kinase 1; mitogen-activated protein kinase 3; MNK1; Mtap2k; p44; p44 MAP kinase; P44ERK1; p44-ERK1; P44MAPK; p44-MAPK; pp42/MAP kinase; PRKM3 | |
Mouse | |
Protein A | |
RUO | |
26417, 50689, 5595 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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