Invitrogen™ ERK2 Recombinant Rabbit Monoclonal Antibody (10C7)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538306

Catalog No. PIMA538306

Description

This antibody has been tested in direct-ELISA.

MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.

Specifications

• Antigen: ERK2
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol, 150 mM NaCl and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P28482, P63085, P63086
• Gene Symbols: MAPK1
• Immunogen: A synthesized peptide derived from human ERK2 (aa 311-360).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 10C7
• Conjugate: Unconjugated
• Gene: MAPK1
• Gene Alias: 9030612K14Rik; AA407128; AU018647; C78273; ERK; ERK2; ERK-2; ERT1; extracellular signal-regulated kinase 2; extracellular signal-regulated kinase-2; extracellular-signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; Mapk; MAPK 1; MAPK 2; Mapk1; MAPK2; mitogen activated protein kinase 1; mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; p38; p40; p41; p41mapk; P42MAPK; p42-MAPK; Prkm1; PRKM2; protein tyrosine kinase ERK2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116590, 26413, 5594
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov