Invitrogen™ ERK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578132

Catalog No. PIPA578132

Description

Positive Control: HeLa, 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, Mal19 Predicted Reactivity: Dog (100%), Pig (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.

Specifications

• Antigen: ERK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAPK1
• Gene Alias: 9030612K14Rik; AA407128; AU018647; C78273; ERK; ERK2; ERK-2; ERT1; extracellular signal-regulated kinase 2; extracellular signal-regulated kinase-2; extracellular-signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; Mapk; MAPK 1; MAPK 2; Mapk1; MAPK2; mitogen activated protein kinase 1; mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; p38; p40; p41; p41mapk; P42MAPK; p42-MAPK; Prkm1; PRKM2; protein tyrosine kinase ERK2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5594
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P28482
• Gene Symbols: MAPK1
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human ERK2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov