Invitrogen™ ERK3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579632

Catalog No. PIPA579632

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Brain Tissue, Rat Skeletal Muscle Tissue, PANC whole cell, NIH3T3 whole cell. IHC: human lung cancer tissue.

The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

Specifications

• Antigen: ERK3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAPK6
• Gene Alias: 2610021I23Rik; D130053K17Rik; DKFZp686F03189; erk3; ERK-3; Erk-3 related; Extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; HsT17250; LOC538094 protein; MAP kinase 6; MAP kinase isoform p97; MAPK 6; Mapk4; Mapk6; Mapk63; mitogen activated protein kinase 4; mitogen activated protein kinase 6; mitogen-activated protein kinase 6; p55-MAPK; p97mapk; p97-MAPK; Prkm4; Prkm6; protein kinase, mitogen activated kinase 4; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6; si:ch211-235f12.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50772, 5597, 58840
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: P27704, Q16659, Q61532
• Gene Symbols: MAPK6
• Immunogen: E.coli-derived human MAPK6 recombinant protein (Position: E520-N721).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov