Invitrogen™ ERK3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA583134

Catalog No. PIPA583134

Description

Immunogen sequence: YSFPMDEPIS SHPFHIEDEV DDILLMDETH SHIYNWERYH DCQFSEHDWP VHNNFDIDEV QLDPRALSDV TDEEEVQVDP RKYLDGDREK YLEDPAFDTN YSTEPCWQYS DHHENKYCDL ECSH.

The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

Specifications

• Antigen: ERK3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAPK6
• Gene Alias: 2610021I23Rik; D130053K17Rik; DKFZp686F03189; erk3; ERK-3; Erk-3 related; Extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; HsT17250; LOC538094 protein; MAP kinase 6; MAP kinase isoform p97; MAPK 6; Mapk4; Mapk6; Mapk63; mitogen activated protein kinase 4; mitogen activated protein kinase 6; mitogen-activated protein kinase 6; p55-MAPK; p97mapk; p97-MAPK; Prkm4; Prkm6; protein kinase, mitogen activated kinase 4; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6; si:ch211-235f12.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5597
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q16659
• Gene Symbols: MAPK6
• Immunogen: Recombinant protein corresponding to Human MAPK6. Recombinant protein control fragment (Product #RP-91423).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG