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Invitrogen™ ERK5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 44688G

Encompass_Preferred

Catalog No. 44-688-G

  • $394.65 / Each of 1

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    Reg : $526.00

    The following deviations and disclosures may produce prices below stated discounts but will not trigger price reductions: Price shown reflects a temporary, promotional price reduction. No other purchase or commercial obligation required to receive the reduced price. Price may change at any time. Promotional price valid on web orders only. Your contract pricing may differ. Other exclusions apply.
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Description

Description

ERK5 Polyclonal Antibody for Western Blot

MAPK7 (ERK5) serine/threonine kinase is a member of the MAP kinase family and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. MAPK7 is activated by mitogen-activated protein kinase 5 (MAP2K5/MEK5) and is involved in downstream signaling processes of various receptors. In response to extracelluar signals, MAPK7 translocates to the cell nucleus where it regulates gene expression by phosphorylating and activating different transcription factors. Gene deletion of MAPK7 in mice results in defective blood vessel and cardiac development leading to embryonic lethality. MAPK7 has been shown to be critical for endothelial function and maintenance of blood vessel integrity. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. ERK5 is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ERK5
Polyclonal
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
P0C865, Q13164, Q9WVS8
MAPK7
The antiserum was produced against a chemically synthesized peptide derived from residues 334-349 of the human ERK5/BMK1 protein. Full-length ERK5/BMK1 has a Mr of ~88 kDa, however, truncated versions of ~30-35 kDa have also been observed.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Western Blot
Unconjugated
MAPK7
Big MAP kinase 1; BMK1; BMK-1; BMK1 kinase; BNhp-1; BNhp1 kinase; ERK4; ERK5; ERK-5; Erk5-T; extracellular signal regulated kinase 5; extracellular signal-regulated kinase 5; extracellular-signal-regulated kinase 5; MAP kinase 7; MAPK 7; Mapk7; mitogen activated protein kinase 7; mitogen-activated protein kinase 7; PRKM7
Rabbit
Antigen Affinity Chromatography
RUO
114509, 23939, 5598
-20°C
Liquid
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