ERK5 Rabbit anti-Human, Clone: 8D8, Bioss

Catalog No.	Quantity
50-198-9563	100 μL

Catalog No. 50-198-9563 Supplier Bioss Supplier No. BSM52069R

Description

Rabbit Monoclonal Antibody

ERK5/MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5. It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver.

Specifications

• Antigen: ERK5
• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 8D8
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
• Gene: MAPK7
• Gene Accession No.: Q13164
• Gene Alias: Big MAP kinase 1; Bmk1; BMK-1; BMK1 kinase; BNhp-1; BNhp1 kinase; ERK4; ERK5; ERK-5; Erk5-T; extracellular signal regulated kinase 5; Extracellular signal-regulated kinase 5; extracellular-signal-regulated kinase 5; MAP kinase 7; MAPK 7; MAPK7; mitogen activated protein kinase 7; Mitogen-activated protein kinase 7; PRKM7
• Gene Symbols: MAPK7
• Host Species: Rabbit
• Immunogen: Recombinant human ERK5 protein, around C-terminal 200aa.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5598
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG